Italian Sub Grilled Cheese (Printable)

A savory Italian-American grilled sandwich loaded with cold cuts, provolone, and a tangy lettuce topping.

# What You'll Need:

→ Bread & Dairy

01 - 4 slices Italian bread or sturdy white sandwich bread
02 - 2 tablespoons unsalted butter, softened
03 - 4 slices provolone cheese

→ Meats

04 - 6 slices salami
05 - 6 slices pepperoni

→ Lettuce Topping

06 - 1 cup shredded iceberg lettuce
07 - 2 tablespoons mayonnaise
08 - 1 tablespoon red wine vinegar
09 - 1 teaspoon dried oregano
10 - Salt and freshly ground black pepper to taste

→ Optional Additions

11 - 2 tablespoons mild pepperoncini rings, drained
12 - 2 tablespoons thinly sliced red onion

# Directions:

01 - In a mixing bowl, combine shredded iceberg lettuce, mayonnaise, red wine vinegar, dried oregano, salt, and freshly ground black pepper. Mix thoroughly and set aside.
02 - Lay out all four bread slices and spread one side of each slice evenly with softened unsalted butter.
03 - Place two buttered bread slices on a work surface with buttered side facing down. Top each slice with 2 slices of provolone cheese, 3 slices of salami, and 3 slices of pepperoni.
04 - If using optional additions, distribute mild pepperoncini rings and thinly sliced red onion evenly over the meat and cheese layers.
05 - Spread the prepared lettuce mixture evenly over the meats and cheese on each sandwich.
06 - Top each sandwich with the remaining bread slices, positioning them with buttered side facing up.
07 - Heat a large skillet or grill pan over medium heat. Place sandwiches in the pan and cook for 3 to 4 minutes per side, gently pressing down, until bread achieves golden color and cheese melts completely.
08 - Remove from heat, slice each sandwich in half diagonally, and serve immediately while hot.

# Expert Suggestions:

01 -
  • The hot crunch of buttery bread meets the cool tang of lettuce slaw in every single bite
  • It comes together in twenty minutes flat but tastes like something from a specialty sandwich shop
  • The lettuce mixture on top is the secret twist that sets this apart from ordinary grilled cheese
02 -
  • Keep the heat at medium, not high, or the bread will burn before the cheese melts completely
  • The lettuce mixture needs to be well drained before adding, or your bread will get soggy fast
03 -
  • Use a panini press if you have one, it creates those signature grill lines and presses everything together evenly
  • Let the sandwiches rest for two full minutes after cooking so the cheese sets slightly
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